General Cell Based Assays
Eurofins Discoverx PathHunter Human LXR beta-NCoR1 Nuclear Receptor Protein Interaction Cell-Based Assay Kit (HEK 293)
The PathHunter Human LXR beta-NCoR1 Nuclear Receptor Stable Cell Line Protein Interaction Assay (HEK 293) contains a stable clonal cell line used to measure activated LXRβ-NCoR1 nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MTNR1A Total GPCR Internalization Cell-Based Assay Kit (DLD1)
The PathHunter Human MTNR1A Stable Cell Line Total GPCR Internalization Assay (DLD1) contains a stable clonal cell line used to measure MTNR1A (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HTR2A (5-HT2A) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR2A (5-HT2A) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HTR2A (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human GPR1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure GPR1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse CTLA4 Signaling Cell-Based Assay Kit (Jurkat)
The PathHunter Mouse CTLA4 (SHP1) Signaling Stable Cell Line Assay (Jurkat) measures CTLA4 signal by recruitment of SH2 domain protein to the activated receptor. Please note this product expresses the mouse version of CTLA-4. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LPS Signaling Reporter Cell-Based Assay Kit (THP-1)
The PathHunter Human LPS Signaling NF-kB Reporter Stable Cell Line Assay (THP-1) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human APRIL (BCMA) Signaling Reporter Cell-Based Assay Kit (K562)
The PathHunter Human APRIL (BCMA) Signaling NF-kB Reporter Stable Cell Line Assay (K562) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC). This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCK2 (CCKBR) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CCK2 (CCKBR) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCKBR (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human VIPR2 Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human VIPR2 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure VIPR2 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human BDKRB2 Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human BDKRB2 Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure BDKRB2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human DRD4 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human DRD4 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure DRD4 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx InCELL Hunter eXpress HEK 293 SMARCA4 Bromodomain Assay, 10-plate Kit. (96-0060E1CP7L)
The InCELL Hunter eXpress HEK 293 SMARCA4 Bromodomain Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of SMARCA4 via detection of SMARCA4 levels. This product uses EFC technology. The cell line included overexpresses SMARCA4 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress HEK 293 BRDT(1,2) Bromodomain Assay, 2-plate Kit. (96-0046E1CP7M)
The InCELL Hunter eXpress HEK 293 BRDT(1,2) Bromodomain Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of BRDT(1,2) via detection of BRDT(1,2) levels. This product uses EFC technology. The cell line included overexpresses BRDT(1,2) target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter IL-15 Bioassay Kit Dimerization 2-plate
PathHunter IL-15 Bioassay Kit Dimerization 2-plate
Meso Scale Discovery R-PLEX Human MMP-13 ASY
The R-Plex Human MMP-13 Assay is a multiplex immunoassay kit from Meso Scale Diagnostics that allows for the quantitative measurement of human Matrix Metalloproteinase 13 (MMP-13) in serum plasma cell culture supernatants cell lysates tissue homogenates and other biological fluids It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay can be used to study MMP-13 levels in research areas like arthritis cancer cardiovascular disease and tissue remodeling With minimal hands-on time this kit allows for rapid profiling of MMP-13 across multiple samples